The University of Zurich and Harvard Medical School Summer School in Clinical Investigation week-long program will help clinicians and clinician-scientists to build skills in clinical investigation with a particular focus on clinical trials, to increase knowledge in statistical analysis, and to connect to a community of like-minded researchers. 

The week-long program includes curriculum sessions on:

  • Novel Trial Design: Sequential and Adaptive Designs 
  • Secondary Analysis of Clinical Trials  
  • Quantitative Methods for Benefit-Harm Analysis 
  • Ethics of Comparative Trials 
  • Statistical Monitoring and Data Monitoring Committees 
Workshops held at the University of Zurich from August 20-24, 2018

Applications are Closed!

The SSCI program is underway.

  • Who Are We Looking For?

    Who should apply for this program?

     Candidates with an MBBS, MD, PhD, DMD, DDS, PharmD, DNP, DPT, RD or equivalent degree with an interest in gaining skills and knowledge in clinical research.

  • Schedule

    Monday August 20

    8:00 AM

    Welcome, Introduction, Team Assignment
    Milo Puhan and Ajay Singh

    8:30 AM

    The Research Question - how to take a hypothesis and study it: Does influenza vaccination influence cardiovascular complications?
    Scott Solomon, HMS

    10:00 AM

    Refreshment Break

    10:30 AM

    Lessons learnt from first and definitive RCTs 
    Marc Pfeffer, HMS

    12:00 PM

    Lunch

    1:00 PM

    Publishing trials – from trial registration to Publishing for impact
    Caren Solomon, HMS

    2:30 PM

    Refreshment Break

    3:00 PM

    Trials: Nuts and Bolts - Statistical Monitoring and DMCs
    Brian Claggett and Marc Pfeffer, HMS

    5:00 PM

    Roundtable Discussion

    5:30 PM

    Class Photo (weather permitting)

    5:30 PM

    Reception

     

    Tuesday August 21

    8:00 AM

    Secondary Analysis of a Clinical Trial: Case Example
    Scott Solomon, HMS

    10:00 AM

    Refreshment Break

    10:30 AM

    Introducing Quantitative Methods for Benefit-Harm Analysis and its Importance for the Planning, Running and Analysis of Trials and Beyond
    Milo Puhan

    12:00 PM

    Lunch

    1:00 PM

    Work on group assignment
    Facilitated by Milo Puhan, Ajay Singh and Brian Claggett

    2:30 PM

    Refreshment Break

    3:00 PM

    Trials: Nuts and Bolts - Power and Sample Size 
    Brian Claggett, HMS

    5:00 PM

    Roundtable Discussion

     

    Wednesday August 22

    8:00 AM

    Trials: Nuts and Bolts -Novel Aproaches to Subgroup Analysis
    Torsten Hothorn, UZH

    10:00 AM

    Refreshment Break

    10:30 AM

    Exercise and discussion of the SUPPORT Study: Comparative Trials
    Ajay Singh, HMS

    12:00 PM

    Lunch

    1:00 PM

    Demonstration/exercise in Quantitative Methods for Benefit-Harm Analysis
    Milo Puhan, Henock Yebyo, Hélène Aschmann, UZH

    2:30 PM

    Refreshment Break

    3:00 PM

    Work on group assignment
    Facilitated by Milo Puhan, Ajay Singh and Brian Claggett

    5:00 PM

    Roundtable Discussion

    7:00 PM

    Social Event

     

    Thursday August 23

    8:00 AM

    Novel Trial Designs: Sequential and Adaptive Trials 
    Marc Vandemeulebroecke, Novartis

    10:00 AM

    Refreshment Break

    10:30 AM

    Work on group assignment
    Facilitated by Milo Puhan, Ajay Singh and Brian Claggett

    12:00 PM

    Lunch
    1:00 PM Survival Analysis in Clinical Trials
    Torsten Hothorn, UZH 

    2:30 PM

    Refreshment Break

    3:00 PM

    Trials: Nuts and Bolts -Defining Study Outcomes That Better Reflect Individual Response to Treatment  
    Brian Claggett, HMS

    5:00 PM

    Roundtable Discussion

     

    Friday August 24

    8:00 AM

    Work on group assignment 
    Facilitated by Milo Puhan, Ajay Singh and Brian Claggett

    10:00 AM

    Refreshment Break
    10:30 AM Team Presentations

    12:00 PM

    Lunch
    1:00 PM Team Presentations

    2:30 PM

    Refreshment Break

    3:00 PM

    Awards and Certificates
  • Admissions

    Application Deadline

    Applications for the 2018 Summer School in Clinical Investigation program are due Wednesday, August 15, 2018, 11:59pm EDT. (lifted from Zurich website)


    Admissions Process

    The review process for applications usually takes 4 – 6 weeks. Please note that only complete applications can be reviewed for acceptance into a program. We strongly encourage you to submit your application as early as possible.


    Eligibility Requirements

    Applicants for the Summer School in Clinical Investigation program must have an MBBS, MD, PhD, DMD, DDS, PharmD, DNP, DPT, RD or equivalent degree to apply.

    The following documents are required to apply for the program:

    • Online application
    • Current Curriculum Vitae/Resume 

    The letter of recommendation can be submitted with your application or at a later date via email to UZHSummer@hms.harvard.edu

  • Faculty

    Hélène Aschmann, MSc
    PhD candidate in Epidemiology
    Epidemiology Biostatistics and Prevention Institute (EBPI)
    University of Zurich

    Brian L. Claggett, PhD
    Instructor in Medicine
    Harvard Medical School
    Chief Statistician
    Cardiac Imaging Core Laboratory and Clinical Trials Endpoints Center
    Brigham and Women's Hospital

    Torsten Hothorn, PhD
    Professor of Biostatistics
    Epidemiology Biostatistics and Prevention Institute (EBPI)
    University of Zurich

    Marc Pfeffer, MD, PHD
    Victor J. Dzau Professor of Medicine
    Brigham and Women’s Hospital

    Milo Puhan, MD, PhD
    Professor of Epidemiology & Public Health
    Director of the Epidemiology Biostatistics and Prevention Institute (EBPI)
    University of Zurich

    Ajay K. Singh, MBBS, FRCP, MBA
    Senior Associate Dean for Global and Continuing Education
    Harvard Medical School

    Scott Solomon, MD
    Professor of Medicine
    Harvard Medical School
    Senior Physician and Director Noninvasive Cardiology
    Brigham and Women's Hospital

    Caren G. Solomon, MD, MPH
    Associate Professor of Medicine
    Harvard Medical School
    Deputy Editor, New England Journal of Medicine

    Marc Vandemeulebroecke, PhD
    Global Group Head
    Integrated Information Sciences
    Novartis

    Henock Yebyo, MSc
    PhD candidate in Epidemiology
    Epidemiology Biostatistics and Prevention Institute (EBPI)
    University of Zurich

  • Want to Learn More?

    Get Access to the latest information and stay up-to-date on program details by completing the form below.